Seasonal variations in nutritional status and oxidative stress in patients on hemodialysis: Are they related?

Seasonal variations in body composition and parameters that reflect nutritional status are well established patients on hemodialysis (HD). However, to our knowledge, no study has assessed the changes oxidative stress (OS). The aims of this were assess seasonal OS, composition, other parameters. fat tissue mass (FTM), index (FTI), adipose (ATM), lean (LTM), (LTI), cell (BCM), overhydration (OH) volume, OS (blood levels derivatives reactive oxygen metabolites [d-ROMs], thiobarbituric substances, plasma protein reduced thiol content [THIOLS], ferric reducing ability plasma) 45 HD, 70 y age (60.5–76.5 y). FTM ( P < 0.001), FTI ATM 0.001) significantly increased, whereas LTI LTM BCM OH volume = 0.004) decreased over season. Additionally, significant d-ROMs 0.02) THIOLS found. Levels found be a predictor (β –0.57; 95% confidence interval [CI], –1.08 –0.06; 0.03; β –0.04; CI, –0.075 –0.006; 0.02). Furthermore, hip circumference was most level 2.66; CI; 0.28–5.04; 0.03) waist-to-height ratio 251; 16.6–477.2; serum prealbumin 263; 6.8–521.1; 0.04). These results suggest HD possible interaction between these patients. • There hemodialysis. is bidirectional correlation parameters, especially those tissue. Oxidative might promoted by could have negative influence mass. Serum antioxidant defense